Four diseases account for most age-related decline. Resonance AI helps you get ahead of them.
Four disease categories drive the majority of decline — and they share the same upstream biology. Resonance AI reasons over each patient's labs, genetics, and intake to surface the drivers early and generate the individualized protocol you deliver.
The reasoning engine behind the Woods framework — built by Lily Woods, PhD.
Most medicine manages disease. Resonance AI works upstream, where it starts.
Test deeper than standard care
Advanced panels and genomics reveal risk years before a routine physical would — while there's still time to change the trajectory.
A protocol built around each patient
Their results, their biology, their goals. Testing drives every recommendation the engine returns — no generic templates, no guesswork.
Measure, intervene, retest
Every pathway is measured, corrected where it drifts, and re-checked. Longevity is a practice you deliver, not a one-time report.
The average American life is 4,000 weeks
Roughly 77 years — and U.S. life expectancy has stagnated over the past decade. The goal isn't only how long patients live, but how much of that time is spent in genuinely good health.
Today's centenarians didn't biohack their way there — most drew a rare genetic advantage, on the order of 1 in 5,000. The work you deliver is different, and it's within reach: keep patients at full function for as long as possible, then compress decline into a short window at the very end. That means catching the conditions that would otherwise surface in a patient's 50s and 60s and delaying them into the 80s and 90s — or preventing them altogether.
Four categories drive more than 80% of age-related mortality in non-smokers.
They're largely addressable with the right interventions — but only if you can see them coming. Here's how the engine reads each one from a patient's data.
ASCVD
Cardiovascular disease and stroke — still the leading cause of death in America by a wide margin, and a major driver of vascular dementia.
- ApoB and Lp(a) — the lipid markers standard panels miss
- Coronary artery calcium (CAC) scoring
- Advanced lipid subfractions and hs-CRP inflammation
- Blood pressure, glycemic and lifestyle risk mapping
Cancer
The earlier it's found, the more options you have. We layer molecular screening over each patient's inherited risk profile.
- Multi-cancer early detection (MCED) blood screening
- Hereditary and genomic risk assessment
- Targeted imaging when results warrant it
- Metabolic and inflammatory terrain markers
Neurodegenerative Disease
What protects the heart protects the brain. We baseline cognition early and track the vascular and metabolic drivers behind it.
- Cognitive baselining and longitudinal tracking
- APOE genotyping and genomic risk
- Neuro-inflammatory and metabolic markers
- Vascular risk shared with the ASCVD workup
Metabolic Dysfunction
Diabetes, fatty liver, and insulin resistance start silently — and quietly fuel the other three horsemen.
- Fasting insulin and HbA1c
- Continuous glucose monitoring (CGM)
- Liver and visceral fat assessment
- Full lipid and inflammatory context
The engine doesn't know a patient's six pathways until it runs their case.
That's the point. The Six Pathway System doesn't sort a patient into a category that already exists — it derives the six pathways driving their biology, from their labs, their genetics, and their full intake, through deep research run on that case specifically.
No two patients get the same six. What comes back isn't a handout with a name on top; it's a program built around what the results actually say, with the reasoning shown so you can stand behind every recommendation you deliver.
Patient data goes in
Labs, genetics, and a full intake — the complete picture, not a snapshot.
Deep research runs on the case
The results are worked against the current evidence, specific to that patient.
The six pathways emerge
The research reveals which pathways are actually driving risk. They're an output, not a menu.
The protocol is designed
A customized program built on those six, with the reasoning behind every recommendation.
How the engine works a case.
Plan with purpose
You outline a path with the patient that's realistic, strategic, and tailored to their situation. The right tests are chosen, then read deeply.
Reasoning you can see
The engine shows its work. Every recommendation carries the evidence behind it — no black boxes, nothing you can't defend.
Design the protocol
With the targets known and the patient's biology mapped, the engine designs exactly what to do next and how progress gets measured.
Remeasure and adapt
As the patient progresses, the protocol adjusts — so the gains hold and the trajectory keeps improving.
Put the engine to work for your patients.
Membership gives you Resonance AI end to end — the reasoning that maps which of the four horsemen matter most for each patient and generates the individualized protocol you deliver.
Precision testing, protocols derived per case, and the reasoning to stand behind every one.